Saccharin is sweeter than sucrose by
(A) 50 times
(B) 100 times
(C) 500 times
(D) 1000 times
How many millilitres of U-100 insulin should be used to obtain 40 units of insulin?
(A) 40 ml
(B) 4 ml
(C) 0.4 ml
(D) 400 ml
In coffee seed, caffeine is present as a salt of
(A) Chlorogenic acid
(B) Lysergic acid
(C) Miconic acid
(D) Uric acid
Prostaglandin analogues in ulcer therapy causes
(A) Diarrhoea
(B) Abortion
(C) Uterine bleeding
(D) All of the above
Oral hypoglycemic agent which is a Thiozolidinedione derivative is
(A) Repaglinide
(B) Glipizide
(C) Pioglitazone
(D) Glimepiride
BCG vaccine is
(A) Live attenuated viral vaccine
(B) Live attenuated bacterial vaccine
(C) Killed bacterial vaccine
(D) Inactivated viral vaccine
The Central Drugs Research Institute at
(A) Kolkata
(B) Kasauli
(C) Izzat Nagar
(D) Lucknow
A receipt given by a seller to a buyer who has returned goods, which can be offset against future purchases
(A) Credit note
(B) Invoice
(C) Debit note
(D) Bill
Which of the following is not a macrolide antibiotic?
(A) Erythromycin
(B) Spiramycin
(C) Azithromycin
(D) Vancomycin
Morphine is present in
(A) Atropa belladonna
(B) Papaver somniferum
(C) Ricinus communis
(D) Solanum nigrum
Autoclaving of ampoules in a dye bath is for
(A) Clarity testing
(B) Pyrogen testing
(C) Leak testing
(D) Sterility testing
Anticancer drugs kill cancer cells by
(A) Zero order kinetics
(B) Pseudo first order kinetics
(C) First order kinetics
(D) Second order kinetics
Dopamine is degraded by
(A) MAO-A
(B) MAO-B
(C) Both (a) and (b)
(D) None of the above
Tyndallization is the process of
(A) Sterilization by heating under pressure for 3 days
(B) Sterilization by heating without pressure for 3 days
(C) Sterilization by heating under pressure for 1 day
(D) None of the above
Which of the following may cause cycloplegia when used topically in the eye?
(A) Cortisone
(B) Physostigmine
(C) Pilocarpine
(D) Atropine
Captopril action by inhibiting conversion of
(A) Angiotensin I to II
(B) Angiotensin II to I
(C) Angiotensinogen to Angiotensin
(D) Angiotensin to Angiotensinogen
The largest peak in a mass spectrum is called as
(A) Parent peak
(B) Daughter peak
(C) Metastable peak
(D) Base peak
Keller kiliani test is the identification test for
(A) Digitalis
(B) Senna
(C) Metformin
(D) Rifampicin
The storage form of Iron in the human body is
(A) Ferritin
(B) Ferrous fumarate
(C) Heme
(D) Globulin
Micromeritics refers to the study of
(A) Microscopes
(B) Micro organisms
(C) Metric system of measurement
(D) Small particles
How many half lives is required to disintegrate 90% of a drug?
(A) 3
(B) 4
(C) 1
(D) 2
A patient with Glucose 6 phosphate dehydrogenase deficiency if treated with Dapsone will develop
(A) Hemolytic anaemia
(B) Pernicious anaemia
(C) Diarrhoea
(D) None of the above
Aztreonam is a
(A) monobactum
(B) Carbapenem
(C) Betalactamase inhibitor
(D) None of the above
DOTS refers to
(A) Divided Option Treatment System
(B) Drug resistance Optimizing Treatment System
(C) Directly Observed Treatment Short course
(D) None of the above
Sublingually used organic nitrate is
(A) Nitroglycerine
(B) Isosorbide dinitrate
(C) Isosorbide mononitrate
(D) Both (a) and (b)
Thromboxane is mainly synthesized by
(A) Lungs
(B) Spleen
(C) Platelets
(D) Endothelium
The Wurster process can be used to
(A) Coat tablets
(B) Determine the disintegration time
(C) Gas sterilize parenteral solutions
(D) Automatic filling of capsules
Emulsions containing more than two phases are called as
(A) Mixed emulsion
(B) Heterogenous emulsion
(C) Homogenized emulsion
(D) Multiple emulsion
The hypotensive effect of Clonidine is due to action on
(A) Alpha adrenergic receptor
(B) Beta adrenergic receptor
(C) H1 receptor
(D) H2 receptor
Antidiabetic agent of choice in diabetic ketoacidosis is
(A) Protamine Zinc Insulin
(B) Isophane Insulin
(C) Crystalline Insulin
(D) Tolbutamide
Black pepper consists of the dried unripe fruits of
(A) Piper betle
(B) Piper cubeba
(C) Piper longum
(D) Piper nigrum
Reddish brown colour of calamine is due to
(A) Zinc chloride
(B) Ferric chloride
(C) Ferric oxide
(D) Potassium permanganate
Disposable syringe are made of
(A) Polypropylene
(B) Glass
(C) Polytetrachloroethylene
(D) None of the above
Which of the following is a physical sunscreen?
(A) TiO2
(B) Para aminobenzoic acid
(C) Methyl salicylate
(D) Silicone oil
Seal coating is applied
(A) To build up the tablet size
(B) To prevent moisture penetration into the tablet core
(C) To round the edges
(D) None of the above
Which Vitamin contain steroidal structure?
(A) Vitamin E
(B) Vitamin A
(C) Vitamin D
(D) Vitamin C
Endothelium dependent relaxing factor of blood
(A) Acetyl choline
(B)Nor adrenaline
(C) Nitric oxide
(D) None of the above
5HT3 antagonist used as anti-emetic agent
(A) Ondansetron
(B)Domperidone
(C) Cisapride
(D) Both (a) and (b)
All the following causes hyperglycemia except
(A) Streptozotocin
(B) Diazoxide
(C) Glucagon
(D) Miglitol
The breakdown of glucose to pyruvic acid is called
(A) Gylcolysis
(B) Glucogenesis
(C) Gylcogenolysis
(D) TCA cycle
Standard for Cosmetics is included in
(A) Schedule P
(B) Schedule T
(C) Schedule S
(D) Schedule F
Poorly manufactured tablets may have small pinholes on the surface. This is called
(A) Mottling
(B) Picking
(C) Leaching
(D) Cracking
The term bioavailability refers to the
(A) Relationship between the physical and chemical properties of a drug and its systemic absorption
(B) Movement of the drug into body tissues over time
(C) Dissolution of a drug in the gastrointestinal tract
(D) Measurement of the rate and amount of the therapeutically active drug that reaches systemic circulation
Selective inhibition of serotonin uptake is by
(A) Desipramine
(B) Fluoxetine
(C) Maprotoline
(D) Lobeline
Largest organ in the body is
(A) Liver
(B) Skin
(C) Bone
(D) Lungs
Which one is the unit of wave number?
(A) Kaiser
(B) Hertz
(C) ms-1
(D) cps
Capacity limited processes can be described by
(A) Linear kinetics
(B) Nonlinear kinetics
(C) Michaelis-Menten kinetics
(D) Mixed kinetics
The cytotoxic drug with maximum emetic activity is
(A) Cisplatin
(B) Chlorambucil
(C) Methotrexate
(D) Busulphan
Liver microsomal enzymes are stimulated by
(A) Cimetidine
(B) Phenobarbitone
(C) Procaine
(D) Adrenaline
Which one of the following is an example of nonionic emulsifying agent ?
(A) Yellow paraffin wax
(B) Bee’s wax
(C) Liquid paraffin
(D) Spans
Rotoweigh is used to measure
(A) Rotation speed of capsules
(B) Weight of capsules
(C) Sorting speed of capsules
(D) None of the above
Solid Fat Index (SFI) is determined by
(A) Potentiometry
(B) Amperometric titration
(C) Voltametry
(D) Dilatometry
Ergotoxine contains
(A) Ergocryptine
(B) Ergocristine
(C) Ergocornine
(D) All of the above
The particles which are deeply bonded, settle rapidly, easily redispersible are known as
(A) Coagules
(B) Defloccules
(C) Floccules
(D) Sediments
Nux vomica seeds contain
(A) Unicellular lignified covering trichomes
(B) Unicellular conical covering trichomes
(C) Unicellular biseriate head
(D) Multicellular unbranched trichomes
The active metabolite of Diazepam
(A) Nitrazepam
(B) Nor Diazepam
(C) Des methyl fluorazepam
(D) None of the above
NSAIDS produce ulcerogenic actions because
(A) They decrease acid secretion in stomach
(B) They increase mucus secretion in stomach
(C) They increase mucosal blood flow in stomach
(D) None of the above
End product pf Purine catabolism in man
(A) Allantoin
(B) Inosine
(C) Uric acid
(D) Xanthine
Asafoetida is obtained from
(A) Afghanistan
(B) Spain
(C) Burma
(D) Malaysia
Liquid paraffin is of
(A) Animal origin
(B) Mineral origin
(C) synthetic origin
(D) Semisynthetic origin
The term MDT (Multi Drug Therapy) is related to
(A) Leprosy
(B) Tuberculosis
(C) Amoebiasis
(D) Giardiasis
Dihydropyridine ring containing Calcium channel blocker is
(A) Verapamil
(B) Diltiazem
(C) Nifedipine
(D) Losartan
To prevent INH induced neurotoxicity, _ is given along with it.
(A) Pyridoxine
(B) Niacin
(C) Cyanocobalamine
(D) Riboflavin
Endotoxin is produced by the following bacteria except
(A) Salmonella typhi
(B) Bordetella pertussis
(C) Yersinia pestis
(D) Clostridium tetani
The drug Amikacin is derived from
(A) Kanamycin
(B) Sisomicin
(C) Gentamicin
(D) Neomycin
The term Amplum denotes
(A) Teblespoonful
(B) Teaspoonful
(C) Dessertspoonful
(D) Wineglassful
Bile is produced by
(A) Gallbladder
(B) Liver
(C) Pancreas
(D) Intestine
morphine does not cause
(A) Constriction of pupil
(B) CNS depression
(C) Respiratory depression
(D) Diarrhoea
Barrier creams are used to protect the skin from
(A) Sunlight injury
(B) Microorganisms
(C) Viral infections
(D) Industrial chemicals and UV rays
Epinephrime is added to local anaesthetics to
(A) Cause haemostasis
(B) Prolong the action of the drug
(C) stimulating healing of wound
(D) Decrease side effects
The phenomenon of repeated administration of a drug resulting in cell receptor blockage is known as
(A) Tachyphylaxis
(B) Idiosynchrosy
(C) Tolerance
(D) Synergism
BAL is used against which metal poisoning?
(A) Copper
(B) Cyanide
(C) Mercury
(D) Iron
An oral hypogylcemic agent which is a Dipeptidyl peptidase-4 inhibitor
(A) Piogliazone
(B) Sitagliptin
(C) Liraglutide
(D) Empagliflozin
A low volume of distribution of a drug indicates
(A) Short biological life
(B) Does not accumulate in various organs
(C) Not bioavailable
(D) None of the above
The mineral deficient in milk
(A) Phosphorous
(B) Sodium
(C) Potassium
(D) Iron
Which of the following monoclonal antibody is fully human in origin?
(A) Daclizumab
(B) Infliximab
(C) Adalimumab
(D) Edrecolomab
Optic neuritis is a side effect of
(A) Sulphasalazine
(B) Rifampicin
(C) Ethambutanol
(D) Pyrazinamide
Which among the following is contra indicated in patients with eGFR less than 15mg/ml/1.75m2?
(A) Insulin
(B) Metformin
(C) Linagliptin
(D) None of the above
Precursor of Thyroxine, epinephrine and nor epinephrine is
(A) Phenyl alanine
(B) Valine
(C) Threonine
(D) Tyrosine
The hardness rings of tablets is usually
(A) 1-2 kg
(B) 0.5-1 kg
(C) 3-7 kg
(D) None of the above