GPAT -2023 Set-3 – PHARMACOLOGY & ALLIED SUBJECTS 28 Questions

1. Which of the following is a nonsteroidal anti-inflammatory drug (NSAID)?
a. Acetaminophen
b. Aspirin
c. Fentanyl
d. Morphine
Answer: b. Aspirin. Aspirin is a NSAID that reduces pain and inflammation.

2. Which of the following is a side effect of corticosteroids?
a. Hypotension
b. Hyperkalemia
c. Hyperglycemia
d. Hypoglycemia
Answer: c. Hyperglycemia. Corticosteroids can increase blood sugar levels, leading to hyperglycemia.

3. Which of the following drug classes is used to treat depression?
a. Beta-blockers
b. Calcium channel blockers
c. Monoamine oxidase inhibitors
d. Diuretics
Answer: c. Monoamine oxidase inhibitors. These drugs are used to treat depression by inhibiting the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine.

4. Which of the following is a drug used to treat hypertension?
a. Nitroglycerin
b. Metoprolol
c. Albuterol
d. Lorazepam
Answer: b. Metoprolol. Metoprolol is a beta-blocker that is commonly used to treat hypertension.

5. Which of the following is a side effect of angiotensin-converting enzyme (ACE) inhibitors?
a. Hypotension
b. Hyperkalemia
c. Hyperglycemia
d. Hypoglycemia
Answer: a. Hypotension. ACE inhibitors can cause hypotension, or low blood pressure.

6. Which of the following is a drug used to treat anxiety?
a. Gabapentin
b. Fluoxetine
c. Alprazolam
d. Sertraline
Answer: c. Alprazolam. Alprazolam is a benzodiazepine that is commonly used to treat anxiety.

7. Which of the following drug classes is used to treat seizures?
a. Antidepressants
b. Antipsychotics
c. Anticonvulsants
d. Antihistamines
Answer: c. Anticonvulsants. These drugs are used to treat seizures by stabilizing the electrical activity in the brain.

8. Which of the following is a side effect of beta-blockers?
a. Hyperkalemia
b. Hypertension
c. Bradycardia
d. Hyperglycemia
Answer: c. Bradycardia. Beta-blockers can cause a slowing of the heart rate, or bradycardia.

9. Which of the following drug classes is used to treat bacterial infections?
a. Antivirals
b. Antifungals
c. Antibiotics
d. Antineoplastics
Answer: c. Antibiotics. These drugs are used to treat bacterial infections by killing or inhibiting the growth of bacteria.

10. Which of the following is a drug used to treat asthma?
a. Albuterol
b. Furosemide
c. Lisinopril
d. Atorvastatin
Answer: a. Albuterol. Albuterol is a bronchodilator that is commonly used to treat asthma.

11. Which of the following is a side effect of statins?
a. Hypoglycemia
b. Hypertension
c. Hyperkalemia
d. Myopathy
Answer: d. Myopathy. Statins can cause muscle damage, or myopathy.

12. Which of the following is NOT an opioid receptor subtype?
a) Mu
b) Delta
c) Kappa
d) Gamma
Answer: d) Gamma. There are only three opioid receptor subtypes: Mu, Delta, and Kappa.

13. Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI)?
a) Venlafaxine
b) Paroxetine
c) Duloxetine
d) Bupropion
Answer: b) Paroxetine. It is a selective serotonin reuptake inhibitor used in the treatment of depression, anxiety disorders, and other conditions.

14. Which of the following drugs is a proton pump inhibitor (PPI)?
a) Omeprazole
b) Ranitidine
c) Famotidine
d) Esomeprazole
Answer: d) Esomeprazole. It is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD), stomach ulcers, and other conditions.

15. Which of the following drugs is an angiotensin receptor blocker (ARB)?
a) Lisinopril
b) Losartan
c) Amlodipine
d) Metoprolol
Answer: b) Losartan. It is an angiotensin receptor blocker used to treat hypertension, diabetic nephropathy, and other conditions.

16. Which of the following drugs is a beta-adrenergic agonist?
a) Albuterol
b) Atenolol
c) Carvedilol
d) Metoprolol
Answer: a) Albuterol. It is a beta-adrenergic agonist used to treat bronchospasm associated with asthma, bronchitis, and other respiratory conditions.

17. Which of the following drugs is a calcium channel blocker?
a) Atenolol
b) Metoprolol
c) Nifedipine
d) Lisinopril
Answer: c) Nifedipine. It is a calcium channel blocker used to treat hypertension, angina, and other conditions.

18. Which of the following drugs is a benzodiazepine?
a) Alprazolam
b) Zolpidem
c) Buspirone
d) Venlafaxine
Answer: a) Alprazolam. It is a benzodiazepine used to treat anxiety disorders, panic disorders, and other conditions.

19. Which of the following drugs is a nonsteroidal anti-inflammatory drug (NSAID)?
a) Acetaminophen
b) Ibuprofen
c) Naproxen
d) Celecoxib
Answer: d) Celecoxib. It is a nonsteroidal anti-inflammatory drug used to treat osteoarthritis, rheumatoid arthritis, and other conditions.

20. Which of the following drugs is a loop diuretic?
a) Furosemide
b) Hydrochlorothiazide
c) Spironolactone
d) Triamterene
Answer: a) Furosemide. It is a loop diuretic used to treat edema associated with heart failure, cirrhosis, and other conditions.

21. Which of the following drugs is a cholinesterase inhibitor?
a) Donepezil
b) Memantine
c) Levodopa
d) Amantadine
Answer: a) Donepezil. It is a cholinesterase inhibitor used to treat Alzheimer’s disease and other conditions.

22. What is the mechanism of action of beta blockers?
a) Inhibit the renin-angiotensin system
b) Block the beta-1 receptors in the heart
c) Increase the production of nitric oxide
d) Enhance the activity of the sympathetic nervous system
Answer: b) Block the beta-1 receptors in the heart
Explanation: Beta blockers work by blocking the beta-1 receptors in the heart, which reduces the heart rate and the force of contraction. This leads to a decrease in the oxygen demand of the heart, making them useful in the treatment of hypertension, angina, and heart failure.

23. Which of the following drugs is used to treat tuberculosis?
a) Isoniazid
b) Rifampicin
c) Streptomycin
d) All of the above
Answer: d) All of the above
Explanation: Isoniazid, rifampicin, and streptomycin are all drugs used in the treatment of tuberculosis. They work by inhibiting the growth and multiplication of the Mycobacterium tuberculosis bacteria.

24. Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI)?
a) Fluoxetine
b) Venlafaxine
c) Bupropion
d) Amitriptyline
Answer: a) Fluoxetine
Explanation: Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression and anxiety disorders. It works by increasing the levels of serotonin in the brain, which improves mood and reduces anxiety.

25. What is the mechanism of action of angiotensin-converting enzyme (ACE) inhibitors?
a) Inhibit the production of aldosterone
b) Block the angiotensin II receptors
c) Inhibit the breakdown of bradykinin
d) Increase the production of nitric oxide
Answer: c) Inhibit the breakdown of bradykinin
Explanation: ACE inhibitors work by inhibiting the breakdown of bradykinin, a substance that causes vasodilation and reduces blood pressure. This leads to a decrease in blood pressure and an improvement in heart function.

26. Which of the following drugs is used to treat malaria?
a) Chloroquine
b) Acyclovir
c) Amphotericin B
d) Metronidazole
Answer: a) Chloroquine
Explanation: Chloroquine is a drug used in the treatment of malaria. It works by interfering with the parasite’s ability to digest and use hemoglobin, which leads to the death of the parasite.

27. What is the mechanism of action of diuretics?
a) Block the beta-1 receptors in the heart
b) Inhibit the renin-angiotensin system
c) Increase the production of nitric oxide
d) Increase the excretion of sodium and water
Answer: d) Increase the excretion of sodium and water
Explanation: Diuretics work by increasing the excretion of sodium and water in the urine, which leads to a reduction in blood volume and a decrease in blood pressure.

28. Which of the following drugs is a calcium channel blocker?
a) Amlodipine
b) Enalapril
c) Losartan
d) Spironolactone
Answer: a) Amlodipine
Explanation: Amlodipine is a calcium channel blocker used in the treatment of hypertension and angina. It works by blocking the influx of calcium ions into the smooth muscle cells of the heart and blood vessels, leading to relaxation of the vessels and a decrease in blood pressure.